Endocrine Abstracts

Rarely does the diagnosis of diabetes go beyond the broad classification of type 1 or type 2 diabetes. This is usually based on simple clinical criteria such as BMI, age of diagnosis and presence of ketosis. We know that approximately 15% of patients are wrongly diagnosed and therefore receive suboptimal treatment. In addition, rarer monogenic forms of diabetes are present in as many as 3% of patients in the paediatric clinic and are often misdiagnosed as type 1 or type 2 diab...

Three premenopausal patients presented with high isolated testosterone without symptoms of androgen excess or illicit drug use.Case 1: A 22-year-old female presented with daily vaginal bleeds having been on depot injections of progesterone with supplementary norethisterone. Testosterone was 14.5 nmol/l with suppressed gonadotrophins (LH <0.1 IU/l, FSH 0.2 IU/l, oestradiol <19 pmol/l). Her norethisterone was stopped. A repeat biochemical profile a...

Hyponatraemia is associated with an increase in morbidity and mortality, prolonged hospital stays and poor assessment and management. Two audits were performed looking at acute medical unit (AMU) admissions with sodium <130 mmol/l, before and after the introduction of a protocol and regular endocrine nurse specialist ward visits, 3 months apart (58 patients in April and 99 in July 2013).Hyponatraemic patients were older than the AMU population (>...